Champalimaud Cancer Talk: Professor Hidde Ploegh

This lecture is part of the "Champalimaud Cancer Talks" series, organised by the Champalimaud Foundation with the aim of offering the general public unique opportunities to hear the world's leading authorities in different fields related to cancer research and clinical practice. This time, Professor Hidde Ploegh will present his research work on:

11 April 2022

International consortium, including CF researchers, finds a way to increase the effectiveness of radiotherapy in brain metastases

The team, headed by Manuel Valiente from CNIO, which counts with the contributions of scientists from other Research Centres, namely the Champalimaud Foundation, found that a simple blood test can help detect patients with resistance to brain radiotherapy and identified a drug that might reverse it. A multi-centre clinical study is now under way to validate the predictive potential of this biomarker through the National Brain Metastasis Network (Spanish acronym: RENACER).

The study is being published in Nature Medicine this week.

07 April 2022

For rectal cancer, our goal is to use the “avatar fish” test to help identify which patients should not be submitted to radiotherapy because their tumour does not respond to radiation

Rita Fior uses zebrafish to do basic and translational research in cancer at the Champalimaud Foundation. A few years ago, having to deal with cancer in her family led her to design a test, based on her animal “model” – that would allow doctors to choose, among the available chemotherapeutic options, the best one for a given patient. How? Using the little zebrafish as “avatars”, as personalised “alter-egos” of the patients. Tumour cells from a patient are injected in the fish, generating the “avatars'' that will then be submitted to the treatment options available for that patient.

30 March 2022

Amongst our patients with rectal cancer submitted to radiotherapy plus chemotherapy, up to a half may have cancers that would disappear completely with potentially no further treatment needed

Interview with Oriol Parés and Bill Heald

Florence Nightingale na Era Digital: “Onde estamos e para onde vamos?"

A Fundação Champalimaud, enquanto instituição prestadora de cuidados na área da oncologia e centro privilegiado de aprendizagem, promove anualmente uma conferência multidisciplinar onde aborda transversalmente o que de mais inovador e diferenciador se faz em oncologia. 

José Bravo Marques

Maria João Rego

Catarina Rosa

Rogelio Andrés-Luna

Sofia Pereira

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